Fatty liver disease is usually linked to a combination of weight, diet, diabetes, cholesterol, and other metabolic problems.

Fatty liver disease, or MASLD (metabolic dysfunction-associated steatotic liver disease), is becoming more common in children and teens. About one in six youth have it, and that number jumps to one in ...

New research shows that the hepatitis B virus X protein T118N mutation, common in Indonesia, increases Cyclin E expression ...

Secondary analysis of the Phase 3 MAESTRO-NASH trial demonstrated Rezdiffra improved histology and MRI-PDFF across common genetic variants ...

CONSHOHOCKEN, PA — Madrigal Pharmaceuticals Inc. (NASDAQ: MDGL) reported that its liver disease drug Rezdiffra improved ...

The TF-rs1049296 T allele interacts with RES iron deposition to identify a MASLD subpopulation at elevated risk of progressive liver disease, providing opportunities for refined risk stratification ...

New insights into how genetic variants in noncoding regions of the genome can contribute to disease risk by disrupting transcription factor (TF) binding have been uncovered. Footprint quantitative ...

A new international study led by Mayo Clinic researchers has identified a genetic factor that may explain why some patients with colorectal cancer that has spread to the liver experience more severe ...

Whole-exome sequencing of liver transplant patients with hepatocellular carcinoma has identified a 13-gene mutation signature ...

The liver is one of the hardest working organs in the human body. It detoxifies harmful substances, helps with digestion, stores nutrients, and regulates metabolism. Despite its remarkable resilience ...

Madrigal Pharmaceuticals, Inc. announced the publication of a pre-specified secondary analysis from the Phase 3 MAESTRO-NASH trial in the Journal of Hepatology evaluating whether common genetic risk ...